Imaging Core Facility (IMFC Biozentrum), University of Basel


Platform manager: Oliver Biehlmaier,, Phone: +41 (0) 61 267 20 73. Address: Biozentrum, University of Basel, Klingerbergstrasse 50 /70. CH- 4056 Basel. Website: Imaging Core Facility (IMCF Biozentrum)


During the past decade the importance of light microscopy increased tremendously in all types of biological research. In addition to the image acquisition at various types of microscopes, data handling and image analysis is becoming more and more important.



Microscopes and support for image analysis is available for all research groups of the Biozentrum


The Imaging Core Facility (IMCF) provides infrastructure for all microscopy techniques currently used in life sciences. The microscopes in the facility span the entire range from standard wide-field microscopy to confocal microscopy and (in the near future) super-resolution microscopy. The newly established facility will start to operate in autumn 2011. Initially there will be 4 point scanning confocal microscopes, 2 spinning disk confocal microscopes, and 2 wide-field microscopes available. The aim of the IMCF is not only to provide the facility users with well-maintained modern microscopy systems as well as with theoretical and technical support but also to develop and adapt new microscopy techniques and image analysis routines.


Areas of interest


Besides the microscopy service for the Biozentrum, research at the IMCF focuses on the development of (i) optimal system performance in terms of image acquisition speed and experimental flexibility thereby enabling users to do all types of experiments under optimal conditions, (ii) image analysis and automation solutions, and (iii) a data storage and database solution (in collaboration with Research IT).


Areas of activity


The IMCF supports projects requiring specific light and fluorescence microscopy setups. Preferably, the IMCF should be involved at every stage: in the planning of a new imaging / microscopy project (selection of fluorescent dyes, choice of microscopy system), during the initial phase (helping with the actual experimental setup including the soft- and hardware settings), and in image analysis and quantification (advice on usage of image analysis software such as Imaris and ImageJ). Only this allows the IMCF to provide the best support at all stages of the project and to adapt the experimental settings to the specific needs.